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North West Leaders Present Northern Arc Vision to Strengthen UK Biotech Connectivity

North West Leaders Present Northern Arc Vision to Strengthen UK Biotech Connectivity

Regional leaders in Greater Manchester and Liverpool City Region are working together to propose a new initiative aimed at improving the UK’s biotech and life sciences infrastructure. Central to the proposal is the development of a new rail link between Liverpool and Manchester, which they argue would enhance collaboration between existing biotech hubs and support future investment in the sector.

The area, referred to as the Northern Arc, spans from the Mersey to the Pennines and includes two designated Investment Zones. The North West already contributes approximately £150 billion in GVA annually, and hosts a growing number of health and life sciences organisations. According to economic studies cited by the mayors, the proposed railway could generate up to £7 billion in additional GVA, support the development of 300,000 new homes, and help create over 40,000 jobs by 2050.

Leaders are working with independent economists to assess the potential for the North West to serve as a nationally significant life sciences cluster. Part of that work includes comparing the region’s potential to the existing Oxford-Cambridge Arc, which is often cited as a successful model for regional innovation and investment in biotech. While no formal conclusions have been published, early indications suggest the Northern Arc could play a complementary role in expanding the UK’s biotech infrastructure.

Existing Life Sciences Activity in the Region

Both city regions are already active in the life sciences space:
In Liverpool City Region, key developments include the £550 million Health Innovation Liverpool campus, the £200 million Infection Innovation Consortium (iiCON), and Sci-Tech Daresbury, a national science and innovation campus with a focus on biotech and digital health.

Greater Manchester hosts projects such as Citylabs, the Old Trafford Regeneration Scheme, and Atom Valley, which combine clinical, academic, and commercial activity.

These sites support a mix of R&D, translational research, and commercial activity, with links to NHS trusts, academic institutions, and international industry partners.

Transport Connectivity as a Limiting Factor
Despite these assets, regional leaders point to limited east-west transport infrastructure as a barrier to greater collaboration and integration. The proposed Liverpool-Manchester railway aims to address this by providing increased capacity and reducing travel times between the two cities and their surrounding research centres.

Improved connectivity could facilitate closer ties between clinical and research institutions, support the mobility of talent, and improve access to key international trade points such as the Port of Liverpool and Manchester Airport.

Next Steps and Governance
To oversee the development of the rail proposal, a Liverpool-Manchester Railway Partnership Board has been established, chaired by former Rail Minister Huw Merriman. The board brings together local government representatives and private sector stakeholders to explore a new governance model for infrastructure delivery, focused on regional input and long-term economic impact.

Potential for National Impact
The Northern Arc concept forms part of broader discussions around regional economic development, infrastructure planning, and the UK’s future role in global biotech. While further analysis is underway, stakeholders suggest that with the right transport links and policy support, the North West could become a stronger contributor to the UK’s life sciences growth strategy.

The project is at an early stage, but it reflects increasing interest in regionally distributed biotech investment and the infrastructure needed to support it.

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